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Too high dose pennicillin question
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Tom A    Posted 05-15-2003 at 02:39:22       [Reply]  [Send Email]
Mornin' all.

I've got a sick goat and a new vet, and I'm a little scared with the treatment. She's 86 pounds (the goat, not the vet) and I'm supposed to giver her 5 cc of penicillin twice a day. In the past, the most I've ever had prescribed was 2.5 cc...and that is much higher than the labelled dosage, but of course a vet can prescribe more. I called back to "doublecheck" that I hadn't misunderstood the dosage and the vet tech went and talked to the vet and reiterated the dose.

Our old large animal vet left the area, so I want to cultivate a relationship with this new one. There is no other in the area. But I also don't want to accidently hurt or kill my goat. She got the one shot last night, and I'll give her a second this morning but I am really scared to give her this second high dose this evening.

What do y'all think?


Cathy in Oregon    Posted 05-15-2003 at 15:20:51       [Reply]  [Send Email]
IMHO your vet is correct.
In cases of extreme illness it is fine to give more than the amount of pen that is recommended on the lable.

I have done it more than once [under advisement by either a vet or my mentor]. I have used the dosage only in cases of life or death.. or in cases of if an infection sets in it will cause death.

I feel that your vet is right on.

thanks to all!    Posted 05-15-2003 at 07:54:35       [Reply]  [No Email]
I appreciate the info. I did call a friend of mine who is a vet (hate to call on friends for stuff like this, but...) and he verified that the dose is high but not excessively so, and there's no problem since she isn't a meat goat.

thanks again to everyone!
Tom A

Ron/PA    Posted 05-15-2003 at 05:20:15       [Reply]  [No Email]
Tom, your biggest concern will be residual retention, not overdose. This could lead to difficulty later on should the goat develope a problem requiring penecillin. In which case you may need to go to higher doses, or an alternate antibiotic. I wouldn't worry about the high level unless it has no effect, then you may have a problem.

Sid    Posted 05-15-2003 at 05:08:13       [Reply]  [No Email]
Vet told me one time the main thing about high pencillan usage was the residual effect in butcher animals, and the fact that sometimes an immunity effect could render it useless in regular doses in the future for that animal.

Salmoneye    Posted 05-15-2003 at 03:38:39       [Reply]  [No Email]

When you say 5cc...What is the concentration of PenVK to fluid?

What does that translate to in mg/dose?

I personally am on the highest dose of PenVK that I have ever been put on for an abcessed tooth at 2000mg/day...

Found this on a Vet dosage site:

*Penicillin G procaine, Penicillin/benzathine: mammals-20,000-40,000 IU/kg IM BID or Q2d for benzathine preparations. Rep-10,000 IU/kg IM Q1-3d for benzathine preparations.
Prototype penicillin antibiotic with narrow gram + and anaerobic spectrum of activity. Resistance is common. Benzathine preparation slows absorption from injection site, thus extending duration of activity. Some argue that absorption is so slow that therapeutic levels are never reached. Aqueous solutions for IV use and oral penicillin V are available.


Tom A    Posted 05-15-2003 at 03:46:37       [Reply]  [Send Email]

Yeah, concentration is a good question. I'm giving her the only concentration I've seen sold in the farm-type stores...300,000 units per ml, and it is identical to the bottle that my former vet sold me a couple of years ago so I'm guessing that vet stuff is all standard (?).

So as I figure it, that is 35,000 units per pound per day. The dosage on the bottle is for meat animals, so I can't really compare.


Salmoneye    Posted 05-15-2003 at 05:36:54       [Reply]  [No Email]
From what I got out of the bit that I posted was that the dose is never all absorbed to an effective level...I think your animal will be fine at the dose the present Vet prescribed...

Cindi    Posted 05-15-2003 at 04:38:24       [Reply]  [No Email]
Sometimes, with a really sick animal the vet will prescribe a really high dose for the first few shots. Are you supposed to decrease the dosage over time?

If you're really concerned I would get a second opinion by calling another vet and just asking what the risks are of the high dosage, or the mfr of the med.

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